Recombinant Human HSC70 Interacting Protein HIP (ab61296)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab61296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

  • Purity> 95 % SDS-PAGE.
    >99% by SDS-PAGE
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: 0.02% None
    Constituents: 250mM Potassium chloride, 20mM MOPS/KOH, 1mM Beta mercaptoethanol, 0.5mM EDTA, pH 7.2

General Info

  • Alternative names
    • AAG 2
    • AAG2
    • Aging associated protein 2
    • F10A1_HUMAN
    • FAM10A1
    • FAM10A4
    • FLJ27260
    • Heat shock 70kD protein binding protein
    • Hip
    • HOP
    • Hsc70 interacting protein
    • Hsc70-interacting protein
    • Hsp70 interacting protein
    • HSPABP
    • HSPABP 1
    • HSPABP1
    • MGC129952
    • OTTHUMP00000028873
    • P48
    • PRO0786
    • Progesterone receptor associated p48 protein
    • Progesterone receptor-associated p48 protein
    • Protein FAM10A1
    • Putative tumor suppressor ST13
    • Renal carcinoma antigen NY REN 33
    • Renal carcinoma antigen NY-REN-33
    • SNC 6
    • SNC6
    • ST 13
    • St13
    • Suppression of tumorigenicity 13
    • Suppression of tumorigenicity 13 (colon carcinoma)
    • Suppression of tumorigenicity 13 protein
    • Suppression of tumorigenicity protein 13
    see all
  • FunctionOne HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins.
  • Sequence similaritiesBelongs to the FAM10 family.
    Contains 1 STI1 domain.
    Contains 3 TPR repeats.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant Human HSC70 Interacting Protein HIP images

  • All lanes : Anti-HSC70 Interacting Protein HIP antibody (ab73917) at 1/250 dilution

    Lane 1 : Recombinant Human HSC70 Interacting Protein HIP (ab61296) at 0.1 µg
    Lane 2 : Recombinant Human HSC70 Interacting Protein HIP (ab61296) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 10 seconds

References for Recombinant Human HSC70 Interacting Protein HIP (ab61296)

ab61296 has not yet been referenced specifically in any publications.

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