3-oxoacyl-acyl-carrier protein reductase, E. coli, homolog of
Beta ketoacyl [acyl carrier protein] reductase like
Estradiol 17 beta dehydrogenase 8
Estradiol 17-beta-dehydrogenase 8
Estrogen 17 oxidoreductase
FabG, E. coli, homolog of
Hydroxysteroid (17 beta) dehydrogenase 8
KE6, mouse homolog of
Really interesting new gene 2 protein
Short chain dehydrogenase/reductase family 30C member 1
Testosterone 17 beta dehydrogenase 8
Testosterone 17-beta-dehydrogenase 8
FunctionNAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol. Has very low activity towards testosterone. The heteroteramer with CBR4 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria.
Tissue specificityHighly expressed in placenta, liver and pancreas, lower in the skeletal muscle and kidney. Widely expressed.