The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Specific activity is approximately < 0.6 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 µmole NADPH per minute at 25°C. Specific activity was expressed as units/mg protein.
>95% by SDS-PAGE .
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
3 alpha HSD1
3-alpha-hydroxysteroid dehydrogenase type I
Aldo keto reductase family 1 member C4
Aldo-keto reductase family 1 member C4
Dihydrodiol dehydrogenase 4
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.