Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMAETDPKTVQ DLTSVVQTLL QQMQDKFQTM SDQIIGRIDD MSSRIDDLEK NIADLMTQAG VEELESENKI PATQKS

Specifications

Our Abpromise guarantee covers the use of ab51233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    This protein was purified to apparent homogeneity by using conventional column chromatography techniques.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 7.5

General Info

  • Alternative names
    • 1500019G21Rik
    • FES1
    • Heat shock protein 70 binding protein
    • Heat shock protein 70 interacting protein
    • Heat shock protein binding protein 1
    • Heat shock protein-binding protein 1
    • Heat-shock 70-KD protein-binding protein 1
    • HPBP1_HUMAN
    • Hsp 70 binding protein
    • Hsp 70 interacting protein
    • Hsp70 binding protein 1
    • Hsp70 binding protein 2
    • Hsp70 interacting protein 1
    • Hsp70 interacting protein 2
    • Hsp70-binding protein 1
    • Hsp70-binding protein 2
    • Hsp70-interacting protein 1
    • Hsp70-interacting protein 2
    • HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
    • HSPA-binding protein 1
    • HSPBP
    • HspBP1
    • HspBP2
    • PP1845
    see all
  • FunctionInhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
  • Tissue specificityUbiquitous.
  • Sequence similaritiesContains 4 ARM repeats.
  • Information by UniProt

Recombinant Human HspBP1 protein images

  • ab51233 run on a 15% SDS-APGE gel with molecular weight markers.

References for Recombinant Human HspBP1 protein (ab51233)

ab51233 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"