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- SourceEscherichia coli
- Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- Additional notes
This protein is suitable for use as a substrate for caspase 3.
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Preparation and Storage
- Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 50% Glycerol, PBS
- Caspase activated deoxyribonuclease inhibitor short form
- DFF 1
- FunctionInhibitor of the caspase-activated DNase (DFF40).
- Sequence similaritiesContains 1 CIDE-N domain.
modificationsCaspase-3 cleaves DFF45 at 2 sites to generate an active factor.
Phosphorylated upon DNA damage, probably by ATM or ATR.
- Cellular localizationCytoplasm.
Information by UniProt
References for Recombinant Human ICAD protein (ab58769)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"