Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab58769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • FormLiquid
  • Additional notes


    This protein is suitable for use as a substrate for caspase 3.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, PBS

General Info

  • Alternative names
    • A330085O09Rik
    • Caspase activated deoxyribonuclease inhibitor short form
    • DFF 1
    • DFF 45
    • DFF alpha
    • DFF-45
    • DFF1
    • DFF35
    • DFF45
    • DFFA
    • Dffa DNA fragmentation factor, alpha subunit
    • DFFA_HUMAN
    • DNA fragmentation factor 45 kDa subunit
    • DNA Fragmentation Factor Alpha Subunit
    • DNA fragmentation factor subunit alpha
    • DNA fragmentation factor, 45 kD, alpha subunit
    • DNA fragmentation factor, 45kDa, alpha polypeptide
    • DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1
    • DNA fragmentation factor, alpha subunit
    • DNAation factor 45 kDa subunit
    • H13
    • ICAD
    • ICAD L
    • ICAD S
    • Inhibitor of CAD
    • Inhibitor of Caspase Activated DNase
    • MGC143066
    • OTTHUMP00000001903
    • OTTHUMP00000001904
    • RP23 121D17.3
    see all
  • FunctionInhibitor of the caspase-activated DNase (DFF40).
  • Sequence similaritiesContains 1 CIDE-N domain.
  • Post-translational
    modifications
    Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Recombinant Human ICAD protein (ab58769)

ab58769 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"