Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      40 kDa including tags
    • Amino acids
      1 to 135
    • Tags
      GST tag N-Terminus

Associated products

Specifications

Our Abpromise guarantee covers the use of ab112306 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    useful for Antibody Production and Protein Array
  • Applications

    SDS-PAGE

    ELISA

    Peptide Array

    Western blot

  • Form
    Liquid
  • Additional notes
    useful for Antibody Production and Protein Array
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced

General Info

  • Alternative names
    • bHLHb26
    • Cell growth inhibiting gene 8
    • class B basic helix loop helix protein 26
    • Class B basic helix-loop-helix protein 26
    • DNA binding protein inhibitor ID 2
    • DNA binding protein inhibitor ID2
    • DNA-binding protein inhibitor ID-2
    • GIG 8
    • GIG8
    • Helix loop helix protein ID2
    • ID2
    • ID2_HUMAN
    • ID2A
    • ID2H
    • Inhibitor of differentiation 2
    • Inhibitor of DNA binding 2
    • Inhibitor of DNA binding 2, dominant negative helix loop helix protein
    • MGC26389
    see all
  • Function
    ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.
  • Tissue specificity
    Highly expressed in early fetal tissues, including those of the central nervous system.
  • Sequence similarities
    Contains 1 basic helix-loop-helix (bHLH) domain.
  • Developmental stage
    Found in most early fetal tissues but not in the corresponding mature tissues.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • ab112306 on 12.5% SDS-PAGE, stained with coomassie blue

References

ab112306 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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