Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ02535
    • SpeciesHuman
    • SequenceMKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSR LRELVPGVPRGTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQ TAELAPELVISNDKRSFCH
    • Molecular weight39 kDa including tags
    • Amino acids1 to 119
    • TagsGST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • FormLiquid
  • Additional notesBest use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

General Info

  • Alternative names
    • 1R21
    • bHLHb25
    • Class B basic helix-loop-helix protein 25
    • DNA binding protein inhibitor ID 3
    • DNA-binding protein inhibitor ID-3
    • HEIR 1
    • HEIR1
    • Helix loop helix protein HEIR 1
    • Helix loop helix protein HEIR1
    • Helix-loop-helix protein HEIR-1
    • HLH642
    • ID 3
    • ID like protein inhibitor HLH 1R21
    • ID like protein inhibitor HLH 462
    • ID-like protein inhibitor HLH 1R21
    • ID3
    • ID3_HUMAN
    • Inhibitor of DNA binding 3
    • Inhibitor of DNA binding 3 dominant negative helix loop helix protein
    see all
  • FunctionID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.
  • Tissue specificityExpressed abundantly in lung, kidney and adrenal gland, but not in adult brain.
  • Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localizationNucleus.
  • Information by UniProt

Recombinant Human ID3 protein images

  • ab112307 analysed on a 12% SDS-PAGE gel stained with coomassie blue.

References for Recombinant Human ID3 protein (ab112307)

ab112307 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"