Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ02535
    • SpeciesHuman
    • SequenceMKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSR LRELVPGVPRGTQLSQVEILQRVIDYILDLQVV
    • Molecular weight35 kDa including tags
    • Amino acids1 to 83

Specifications

Our Abpromise guarantee covers the use of ab114366 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 1R21
    • bHLHb25
    • Class B basic helix-loop-helix protein 25
    • DNA binding protein inhibitor ID 3
    • DNA-binding protein inhibitor ID-3
    • HEIR 1
    • HEIR1
    • Helix loop helix protein HEIR 1
    • Helix loop helix protein HEIR1
    • Helix-loop-helix protein HEIR-1
    • HLH642
    • ID 3
    • ID like protein inhibitor HLH 1R21
    • ID like protein inhibitor HLH 462
    • ID-like protein inhibitor HLH 1R21
    • ID3
    • ID3_HUMAN
    • Inhibitor of DNA binding 3
    • Inhibitor of DNA binding 3 dominant negative helix loop helix protein
    see all
  • FunctionID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.
  • Tissue specificityExpressed abundantly in lung, kidney and adrenal gland, but not in adult brain.
  • Sequence similaritiesContains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localizationNucleus.
  • Information by UniProt

Recombinant Human ID3 protein images

  • 12.5% SDS-PAGE showing ab114366 at approximately 34.76kDa stained with Coomassie Blue.

References for Recombinant Human ID3 protein (ab114366)

ab114366 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114366.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"