Recombinant Human IGFBP5 protein (ab190386)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MASMTGGQQMGRGHHHHHHGNLYFQGGEFLGSFVHCEPCDEKALSMCPPS PLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLH ALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKH TRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGP CRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGIC WCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
    • Molecular weight
      32 kDa including tags
    • Amino acids
      20 to 272
    • Additional sequence information
      Expressed with a T7-His-TEV cleavage site Tag (29aa) fusion at the N-terminal.

Specifications

Our Abpromise guarantee covers the use of ab190386 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    >90% by SDS-PAGE.
    ab190386 was refolded using temperature shift inclusion body refolding technology and chromatographically purified.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituent: 0.32% Tris HCl

    Contains NaCl, KCl, EDTA, arginine, DTT and Glycerol.

General Info

  • Alternative names
    • IBP 5
    • IBP-5
    • IBP5
    • IBP5_HUMAN
    • IGF binding protein 5
    • IGF BP5
    • IGF-binding protein 5
    • IGFBP 5
    • IGFBP-5
    • IGFBP5
    • Insulin like growth factor binding protein 5
    • Insulin-like growth factor-binding protein 5
    see all
  • Function
    IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • Tissue specificity
    Osteosarcoma, and at lower levels in liver, kidney and brain.
  • Sequence similarities
    Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab190386 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab190386.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up