The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
IKAROS family zinc finger 5 (Pegasus)
Ikaros family zinc finger protein 5
Zinc finger protein Pegasus
Zinc finger protein subfamily 1A 5
Zinc finger transcription factor Pegasus
DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence. Transcriptional repressor.
Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K562. Highly expressed in THP-1 and Mo7e-IL3 cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.
Belongs to the Ikaros C2H2-type zinc-finger protein family. Contains 5 C2H2-type zinc fingers.
The N-terminal zinc fingers are involved in sequence-specific DNA binding and heterotypic associations with other family members. C-terminal zinc fingers mediate homodimerization.