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Source Escherichia coli
Amino Acid Sequence
Sequence MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
Molecular weight 19 kDa
Additional sequence information Interleukin-10 Human Recombinant produced in E.coli is a single non-glycosylated polypeptide chains containing 161 amino acids each and having a molecular mass of 18.6kDa. Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 95
% SDS-PAGE. ab73609 purified by proprietary chromatographic techniques.
Purity is greater than 95% as determined by RP-HPLC and SDS-PAGE.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitution Reconstitute in sterile 18MO-cm H 2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Cytokine synthesis inhibitory factor
Function Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.
Tissue specificity Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.
Sequence similarities Belongs to the IL-10 family.
Cellular localization Secreted.
Information by UniProt
References for Recombinant human IL10 protein (ab73609)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"