The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
The ED50 of recombinant Human IL17, as determined by the production of IL6 by NIH3T3 cells, was typically found to be 3-15 ng/ml.
% SDS-PAGE. ab119440 is purified by proprietary chromatographic techniques.
Endotoxin level is <0.1 ng/µg.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Centrifuge the vial prior to opening. Reconstitute with sterile water to a concentration of 0.1 mg/ml, the solution can then be diluted into other aqueous buffers.
For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA).
Cytotoxic T lymphocyte associated antigen 8
CYTOTOXIC T LYMPHOCYTE ASSOCIATED SERINE ESTERASE 8
mutant IL 17F
IL17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis.
IL17A induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.
has not yet been referenced specifically in any publications.
Publishing research using ab119440? Please let us know so that we can cite the reference in this datasheet.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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