Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP60568
    • SpeciesHuman
    • Molecular weight16 kDa
    • Amino acids21 to 153

Associated products

Specifications

Our Abpromise guarantee covers the use of ab119439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity>1 x 107 units/mg as determined by dose­-dependent stimulation of CTLL­2 cells.
  • Applications

    Western blot

    ELISA

    Functional Studies

    SDS-PAGE

    HPLC

  • Purity> 95 % SDS-PAGE.
    Purity >98% by SDS PAGE and HPLC sequence analysis.
  • FormLyophilised
  • Additional notesPrior to reconstitution store at +4°C. >1 x 107 units/mg as determined by dose­-dependent stimulation of CTLL­2 cells.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitute with 0.1ml 0.1M acetic acid. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.

General Info

  • Alternative names
    • Aldesleukin
    • IL 2
    • IL-2
    • IL2
    • IL2_HUMAN
    • Interleukin 2
    • Interleukin-2
    • Involved in regulation of T cell clonal expansion
    • Lymphokine
    • OTTHUMP00000164090
    • POIL2
    • T Cell Growth Factor
    • T-cell growth factor
    • TCGF
    see all
  • FunctionProduced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
  • Involvement in diseaseNote=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
  • Sequence similaritiesBelongs to the IL-2 family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant human IL2 protein (ab119439)

ab119439 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119439.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"