The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. > 95% by SDS-PAGE and HPLC analyses
Endotoxin level: < 0.1 ng per µg of IL2 Receptor alpha
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
ReconstitutionWe recommended a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted into other aqueous buffers.
Interleukin 2 receptor alpha chain
IL 2 receptor alpha subunit
IL-2 receptor subunit alpha
IL-2R subunit alpha
IL2R, alpha chain
Interleukin 2 receptor
Interleukin 2 receptor alpha
Interleukin-2 receptor subunit alpha
t-cell growth factor receptor
FunctionReceptor for interleukin-2.
Involvement in diseaseGenetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.