Recombinant Human IL36 gamma protein (ab167874)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSMRGTPGD ADGGGRAVYQ SMCKPITGTI NDLNQQVWTL QGQNLVAVPR SDSVTPVTVA VITCKYPEAL EQGRGDPIYL GIQNPEMCLY CEKVGEQPTL QLKEQKIMDL YGQPEPVKPF LFYRAKTGRT STLESVAFPD WFIASSKRDQ PIILTSELGK SYNTAFELNI ND
    • Molecular weight
      21 kDa including tags
    • Amino acids
      1 to 169
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab167874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    >90% by SDS-PAGE.
    purified by using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris-HCl buffer, 10% Glycerol, 0.88% Sodium chloride

General Info

  • Alternative names
    • IL 1 epsilon
    • IL 1 related protein 2
    • IL 1(EPSILON)
    • IL 1F9
    • IL 1H1
    • IL 1RP2
    • IL-1 epsilon
    • IL-1-related protein 2
    • IL-1F9
    • IL-1H1
    • IL-1RP2
    • IL1E
    • Il1f9
    • IL1F9_HUMAN
    • IL1H1
    • IL1RP2
    • IL36G
    • Interleukin 1 epsilon
    • Interleukin 1 family member 9
    • Interleukin 1 homolog 1
    • Interleukin 1 related protein 2
    • Interleukin 36 gamma
    • Interleukin-1 epsilon
    • Interleukin-1 family member 9
    • Interleukin-1 homolog 1
    see all
  • Function
    Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response.
  • Tissue specificity
    Highly expressed in tissues containing epithelial cells: skin, lung, stomach and esophagus. In skin is expressed only in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Up-regulated in lesional psoriasis skin.
  • Sequence similarities
    Belongs to the IL-1 family.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of ab167874 (3µg)

References

ab167874 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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