The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% by SDS-PAGE. ab99519 was purified using conventional chromatography.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
Inositol 1(or 4) monophosphatase
Inositol monophosphatase 1
Inositol(myo) 1(or 4) monophosphatase 1
Inositol-1(or 4)-monophosphatase 1
Lithium sensitive myo inositol monophosphatase A1
Lithium-sensitive myo-inositol monophosphatase A1
FunctionResponsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
PathwayPolyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.
Sequence similaritiesBelongs to the inositol monophosphatase family.