Recombinant human Insulin Receptor R protein (ab69988)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • AccessionP14616
    • SpeciesHuman
    • Molecular weight65 kDa
    • TagsGST tag N-Terminus
    • Additional sequence informationRecombinant human fragment of Insulin Receptor R (945-end).

Associated products

Specifications

Our Abpromise guarantee covers the use of ab69988 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific activity: 111 nmol/min/mg as per kinase assay.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.

  • FormLiquid
  • Additional notes

    ab204853 (IRS1 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • INSRR
    • INSRR_HUMAN
    • Insulin receptor related receptor precursor
    • Insulin receptor-related protein alpha chain
    • Insulin receptor-related protein beta chain
    • insulin receptor-related receptor
    • IR R
    • IR related receptor
    • IR-related receptor
    • IRR
    • Sir r
    • Sirr
    see all
  • FunctionThis receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 3 fibronectin type-III domains.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt

Recombinant human Insulin Receptor R protein images

  • Insulin Receptor R enzymatic activity.
  • SDS page analysis of ab69988

References for Recombinant human Insulin Receptor R protein (ab69988)

ab69988 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your recent telephone enquiry.

I am sorry to confirm, as we discussed on the telephone, that ab69988 Insulin Receptor R protein has not been tested and guaranteed in binding assays, and has not been tested with ab123768 insulin...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"