Recombinant Human IQSEC1 protein (ab160717)

Overview

  • Product name
    Recombinant Human IQSEC1 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVL SNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVSPECGDLSEPTT LKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHTEEAPALD AARARDTEPQTALHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAG DRPSSTESDLRLRAGGAAPDYWALAHKEDKADTDTSCRSTPSLERQEQRL RVEHLPLLTIEPPSDSSVDLSDRSERGSLKRQSAYERSLGGQQGSPKHGP HSGAPKSLPREEPELRPRPPRPLDSHLAINGSANRQSKSESDYSDGDNDS INSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKEARNSWDSPAFSNDV IRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQ MIGEFLGNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQ KVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVK PERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERIRKRELKTNEDHVSQV QKVEKLIVGKKPIGSLHPGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLG LHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYP NGIRLTSSVPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQEMEKHRI ESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSAL SSSLRDLSEAGVHH
    • Amino acids
      1 to 814
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab160717 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • ADP-ribosylation factors guanine nucleotide-exchange protein 100
    • ADP-ribosylation factors guanine nucleotide-exchange protein 2
    • ARF GEP100
    • ARFGEP100
    • BRAG2
    • Brefeldin A resistant ARF GEF2
    • Brefeldin-resistant Arf-GEF 2 protein
    • GEP100
    • IQ motif and Sec7 domain 1
    • IQ motif and SEC7 domain-containing protein 1
    • IQEC1_HUMAN
    • Iqsec1
    • Kiaa0763
    see all
  • Function
    In addition to accelerate GTP gamma S binding by ARFs of all three classes, it appears to function preferentially as a guanine nucleotide exchange protein for ARF6, mediating internalisation of beta-1 integrin.
  • Tissue specificity
    Expressed in brain, ovary, heart, lung, liver, kidney and leukocytes. Moderate expression was also detected in lung, skeletal muscle, placenta, small intestine, pancreas, spleen and testis.
  • Sequence similarities
    Belongs to the BRAG family.
    Contains 1 IQ domain.
    Contains 1 PH domain.
    Contains 1 SEC7 domain.
  • Cellular localization
    Cytoplasm. Nucleus. At steady state, may be preferentially cytosolic.
  • Information by UniProt

Images

  • ab160717 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab160717 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab160717.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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