Overview

Description

  • Nature
    Recombinant
  • Source
    Saccharomyces cerevisiae
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MAGSREVVAM DCEMVGLGPH RESGLARCSL VNVHGAVLYD KFIRPEGEIT DYRTRVSGVT PQHMVGATPF AVARLEILQL LKGKLVVGHD LKHDFQALKE DMSGYTIYDT STDRLLWREA KLDHCRRVSL RVLSERLLHK SIQNSLLGHS SVEDARATME LYQISQRIRA RRGLPRLAVS D

Associated products

Specifications

Our Abpromise guarantee covers the use of ab88203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5

General Info

  • Alternative names
    • CD25
    • Estrogen regulated transcript 45 protein
    • Estrogen-regulated transcript 45 protein
    • HEM45
    • Interferon stimulated exonuclease gene 20kDa
    • Interferon stimulated gene 20 kDa protein
    • Interferon-stimulated gene 20 kDa protein
    • Isg20
    • ISG20_HUMAN
    • Promyelocytic leukemia nuclear body associated protein
    • Promyelocytic leukemia nuclear body-associated protein ISG20
    see all
  • Function
    Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.
  • Tissue specificity
    Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung.
  • Sequence similarities
    Belongs to the exonuclease superfamily.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab88203 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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