The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Jumonji domain containing 1C
Jumonji domain-containing protein 1C
Probable JmjC domain-containing histone demethylation protein 2C
Thryoid receptor interacting protein
Thyroid receptor-interacting protein 8
TR-interacting protein 8
Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes.
Belongs to the JHDM2 histone demethylase family. Contains 1 JmjC domain.
Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
Phosphorylated upon DNA damage, probably by ATM or ATR.