Recombinant Human UFL1 protein (ab161615)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
Description
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Product name
Recombinant Human UFL1 protein -
Expression system
Wheat germ -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MADAWEEIRRLAADFQRAQFAEATQRLSERNCIEIVNKLIAQKQLEVVHT LDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLIHIENRIGDI IKSEKHVQLVLGQLIDENYLDRLAEEVNDKLQESGQVTISELCKTYDLPG NFLTQALTQRLGRIISGHIDLDNRGVIFTEAFVARHKARIRGLFSAITRP TAVNSLISKYGFQEQLLYSVLEELVNSGRLRGTVVGGRQDKAVFVPDIYS RTQSTWVDSFFRQNGYLEFDALSRLGIPDAVSYIKKRYKTTQLLFLKAAC VGQGLVDQVEASVEEAISSGTWVDIAPLLPTSLSVEDAAILLQQVMRAFS KQASTVVFSDTVVVSEKFINDCTELFRELMHQKAEKEMKNNPVHLITEED LKQISTLESVSTSKKDKKDERRRKATEGSGSMRGGGGGNAREYKIKKVKK KGRKDDDSDDESQSSHTGKKKPEISFMFQDEIEDFLRKHIQDAPEEFISE LAEYLIKQV -
Amino acids
1 to 509 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab161615 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Western blot
ELISA
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Form
Liquid -
Additional notes
This product was previously labelled as K0776.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- E3 UFM1-protein ligase 1
- KIAA0776
- LZAP-binding protein
see all -
Function
E3 UFM1-protein ligase that mediates ufmylation of target proteins such as DDRGK1/C20orf116. The function of ufmylation is unknown. May act as a tumor suppressor by inhibiting cell invasion, blocking NF-kappa-B signaling and increasing stability of CDK5RAP3. -
Tissue specificity
Ubiquitously expressed, with a high expression in liver (at protein level). Low expression in several invasive hepatocellular carcinomas, such HepG2, Hep3B, HLE and PLC. -
Sequence similarities
Belongs to the UFL1 family. -
Post-translational
modificationsUbiquitinated, leading to its degradation by the proteasome. Interaction with CDK5RAP3 protects each other against ubiquitination and degradation via the proteasome. -
Cellular localization
Endoplasmic reticulum. Cytoplasm. In cytoplasm colocalizes with CDK5RAP3. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab161615 has not yet been referenced specifically in any publications.