Recombinant human Kallikrein 1 protein (ab117200)

Overview

Description

  • NatureRecombinant
  • SourceYeast
  • Amino Acid Sequence
    • AccessionP06870
    • SpeciesHuman
    • Molecular weight28 kDa
    • Amino acids25 to 262

Specifications

Our Abpromise guarantee covers the use of ab117200 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityHuman Kallikrein 1 active. Unit Definitin: 1 unit will hydrolize 1 umole of H-D-Val-Leu-Arg-pNA per minute at pH 8.0 at 37°C Human Kallikrein 1 measured biological activity of no less than 5 Units/mg
  • Applications

    HPLC

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    ab117200 is purified by proprietary chromatographic techniques.
  • FormLyophilised
  • Additional notesalthough stable at 4°C for 3 weeks, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Constituent: 100% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionIt is recommended to reconstitute the lyophilized KLK1 in sterile 18MO-cm H2O not less than 100 µg/ml or more than 10 mg/ml solutions.

General Info

  • Alternative names
    • Glandular kallikrein 1
    • hK 1
    • hK1
    • Kallikrein serine protease 1
    • Kallikrein-1
    • Kidney/pancreas/salivary gland kallikrein
    • Klk 6
    • KLK1
    • KLK1_HUMAN
    • Klk6
    • KLKR
    • Tissue kallikrein
    see all
  • FunctionGlandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
  • Tissue specificityIsoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.
  • Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily.
    Contains 1 peptidase S1 domain.
  • Post-translational
    modifications
    The O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located.
  • Information by UniProt

References for Recombinant human Kallikrein 1 protein (ab117200)

ab117200 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab117200.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"