Recombinant Human KAT9 / Elp3 protein (ab105858)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      86 kDa
    • Amino acids
      1 to 547

Specifications

Our Abpromise guarantee covers the use of ab105858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • Purity
    > 75 % Densitometry.
    ab105858 was determined to be >75% pure by densitometry.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Sodium chloride, 50mM Tris HCl, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

General Info

  • Alternative names
    • DKFZp761L098
    • Elongation protein 3 homolog
    • Elongation protein 3 homolog (S. cerevisiae)
    • ELONGATION PROTEIN 3, S. CEREVISIAE, HOMOLOG OF
    • elongator acetyltransferase complex subunit 3
    • Elongator complex protein 3
    • elp3
    • ELP3_HUMAN
    • FLJ10422
    • hELP3
    • Hypothetical protein DKFZp761L098
    • Kat9
    see all
  • Function
    Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity.
  • Sequence similarities
    Belongs to the ELP3 family.
    Contains 1 N-acetyltransferase domain.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • ab105858 was determined to be >75% pure by densitometry.

References

ab105858 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

The lab have confirmed that under our own assay conditions, SIRT4 (ab101713) and KAT9(ELP3) (ab105858) proteins have not shown significant activity and that is why we have not labeled them as active. However, some phosphorylation may be present as we d...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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