Overview

  • Product nameRecombinant Human KCNA3 protein
  • Protein lengthProtein fragment

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • Accessionp22001
    • SpeciesHuman
    • SequenceVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLS KSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
    • Molecular weight37 kDa including tags
    • Amino acids476 to 575

Specifications

Our Abpromise guarantee covers the use of ab114518 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • HGK 5
    • HGK5
    • HLK 3
    • HLK3
    • HPCN 3
    • HPCN3
    • HuKIII
    • KCNA 3
    • Kcna3
    • KCNA3_HUMAN
    • KV1.3
    • MK 3
    • MK3
    • OTTHUMP00000032397
    • PCN 3
    • PCN3
    • Potassium channel 3
    • Potassium voltage gated channel shaker related subfamily member 3
    • Potassium voltage gated channel subfamily A member 3
    • Potassium voltage-gated channel subfamily A member 3
    • Type n potassium channel
    • Voltage gated potassium channel protein Kv1.3
    • Voltage gated potassium channel subunit Kv1.3
    • Voltage-gated K(+) channel HuKIII
    • Voltage-gated potassium channel subunit Kv1.3
    see all
  • FunctionMediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • Sequence similaritiesBelongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
  • DomainThe N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localizationMembrane.
  • Information by UniProt

Recombinant Human KCNA3 protein images

  • ab114518 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

References for Recombinant Human KCNA3 protein (ab114518)

ab114518 has not yet been referenced specifically in any publications.

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