The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityuseful for Antibody Production and Protein Array
Additional notesuseful for Antibody Production and Protein Array
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl Note: Glutathione is reduced
Histone demethylase JARID1A
Jumonji/ARID domain containing protein 1A
Jumonji/ARID domain-containing protein 1A
Lysine-specific demethylase 5A
Retinoblastoma binding protein 2
Retinoblastoma-binding protein 2
FunctionHistone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12.