Recombinant Human KDM6A / UTX protein (ab159790)
Key features and details
- Expression system: Wheat germ
- Purity: >= 80% Purified via GST Tag
- Tags: GST tag N-Terminus
- Suitable for: SDS-PAGE, ELISA, WB
Description
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Product name
Recombinant Human KDM6A / UTX protein
See all KDM6A / UTX proteins and peptides -
Purity
>= 80 % Purified via GST Tag.
Glutathione Sepharose -
Expression system
Wheat germ -
Accession
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Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
QGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSV TQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNS -
Amino acids
641 to 740 -
Tags
GST tag N-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab159790 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
ELISA
Western blot
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Form
Liquid -
Additional notes
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
General Info
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Alternative names
- bA386N14.2
- bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX)
- bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX
see all -
Function
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. -
Sequence similarities
Belongs to the UTX family.
Contains 1 JmjC domain.
Contains 8 TPR repeats. -
Cellular localization
Nucleus. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab159790 has not yet been referenced specifically in any publications.