Recombinant Human KIR3DL1 protein (ab51218)

Overview

  • Product name
    Recombinant Human KIR3DL1 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSTSGT IDKLDIEFHL WCSNKKNAAV MDQEPAGNRT ANSEDSDEQD PEEVTYAQLD HCVFTQRKIT RPSQRPKTPP TDTILYTELP NAKPRSKVVS CP
    • Molecular weight
      15 kDa including tags
    • Amino acids
      361 to 444
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab51218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    A His-tag fusion protein of KIR3DL1 cytoplasmic tail was overexpressed as insoluble protein aggregates (inclusion bodies). This protein was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer.
  • Form
    Liquid
  • Additional notes


    The cytoplasmic tail of KIR3DL1, which contains two immunoreceptor tyrosine-based inhibition motifs (ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25mM Tris HCl, 100mM Sodium chloride, pH 7.5

General Info

  • Alternative names
    • AMB11
    • CD158 antigen-like family member E
    • CD158e
    • CD158e antigen
    • CD158E1
    • CD158E1/2
    • CD158E2
    • CL11
    • CL2
    • HLA-BW4-specific inhibitory NK cell receptor
    • KI3L1_HUMAN
    • killer cell immunoglobulin like receptor
    • Killer cell immunoglobulin like receptor three domains , short cytoplasmic tail, 1
    • Killer cell immunoglobulin like receptor three domains long cytoplasmic tail 1
    • Killer cell immunoglobulin-like receptor 3DL1
    • KIR
    • KIR antigen 3DL1
    • KIR G1
    • Kir3dl1
    • KIR3DS1
    • Kirl1
    • Kirl2
    • Krl1
    • MGC119726
    • MGC119728
    • MGC126589
    • MGC126591
    • MHC class I NK cell receptor
    • Natural killer associated transcript 3
    • Natural killer cell inhibitory receptor
    • Natural killer-associated transcript 3
    • NK receptor
    • NK-associated transcript 10
    • NK-associated transcript 3
    • NK-associated transcript 3delIg1
    • NKAT-3
    • NKAT10
    • NKAT3
    • NKB1
    • NKB1B
    • p70 killer cell inhibitory receptor
    • p70 natural killer cell receptor clones CL 2/CL 11
    • p70 natural killer cell receptor clones CL-2/CL-11
    • p70 NK receptor CL-2/CL-11
    see all
  • Function
    Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis.
  • Sequence similarities
    Belongs to the immunoglobulin superfamily.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
  • Cellular localization
    Cell membrane.
  • Information by UniProt

Recombinant Human KIR3DL1 protein images

  • 14% SDS-PAGE gel loaded with ab51218, recombinant human KIR3DL1 protein (His tag).
    Predicted molecular weight 15kDa.

References for Recombinant Human KIR3DL1 protein (ab51218)

ab51218 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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