Overview

  • Product nameRecombinant Human KRT81 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionAAH21241
    • SpeciesHuman
    • SequenceMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC QNSKLEAAVA QSEQQGEAALSDARCKLAELEGALQKA KQDMACLIREYQEVMNSKLGL DIEIATYRRLLEGEEQR LCEGIGAVNVCVSSSRGGVVCGDLCVSGSRP VTGSV CSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSC GISSL GVGSCGSSCRKC
    • Molecular weight48 kDa including tags
    • Amino acids1 to 202
    • Tagsproprietary tag N-Terminus

Associated products

Specifications

Our Abpromise guarantee covers the use of ab117016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

    ELISA

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 1
    • basic
    • ghHb 1
    • ghHb1
    • ghHkb 1
    • ghHKb1
    • hair
    • Hair keratin K2.9
    • Hard keratin type II 1
    • HB 1
    • HB1
    • hHAKB2 1
    • K2.9
    • K81
    • Keratin
    • Keratin 81
    • Keratin hair basic 1
    • Keratin type II cuticular Hb1
    • Keratin-81
    • Keratin81
    • KRT 81
    • KRT81
    • KRT81_HUMAN
    • KRTHB 1
    • KRTHB1
    • Metastatic lymph node 137 gene protein
    • MLN 137
    • MLN137
    • type II cuticular Hb1
    • Type II hair keratin Hb1
    • Type-II keratin Kb21
    see all
  • Tissue specificityAbundantly expressed in the differentiating cortex of growing (anagen) hair. Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla. Expressed in malignant lymph node tissue in breast carcinoma tissue.
  • Involvement in diseaseDefects in KRT81 are a cause of monilethrix (MLTRX) [MIM:158000]. Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected.
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Information by UniProt

Recombinant Human KRT81 protein images

  • 12.5% SDS-PAGE showing ab117016 at approximately 48.33 kDa.
    Stained with Coomassie Blue.

References for Recombinant Human KRT81 protein (ab117016)

ab117016 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"