Up to 0.2 µg/ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (FACS).
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
pH: 7.10 Constituent: 99% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionReconstitute in 40 µl of ultra-pure distilled H2O. This solution can then be diluted into other aqueous buffers and stored at –20°C or –70°C for future use.
BPI fold containing family D, member 2
Lipopolysaccharide binding protein
LPS binding protein
FunctionBinds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. The LBP/LPS complex seems to interact with the CD14 receptor.
Sequence similaritiesBelongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.