Overview

  • Product name
    Recombinant Human LDB1 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MLDRDVGPTPMYPPTYLEPGIGRHTPYGNQTDYRIFELNKRLQNWTEECD NLWWDAFTTEFFEDDAMLTITFCLEDGPKRYTIGRTLIPRYFRSIFEGGA TELYYVLKHP
    • Amino acids
      1 to 110
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab152925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Carboxyl Terminal LIM Domain Binding 2
    • Carboxyl-terminal LIM domain-binding protein 2
    • CLIM 2
    • CLIM-2
    • hLdb1
    • LDB-1
    • ldb1
    • LDB1_HUMAN
    • LIM Domain Binding 1
    • LIM domain binding factor CLIM2
    • LIM domain-binding factor CLIM2
    • LIM domain-binding protein 1
    • NLI
    • Nuclear LIM Domain Interactor
    • Nuclear LIM interactor
    • xldb1
    see all
  • Function
    Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a role in the development of motor neurons. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state.
  • Tissue specificity
    Expressed in a wide range of adult tissues including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, lung and peripheral blood leukocytes.
  • Sequence similarities
    Belongs to the LDB family.
  • Domain
    The dimerization domain is located in the N-terminus.
  • Post-translational
    modifications
    Ubiquitinated by RLIM/RNF12, leading to its degradation by the proteasome.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • ab152925 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab152925 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab152925.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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