The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Endotoxin level< 0.100 Eu/µg
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Preparation and Storage
Stability and Storage
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
ReconstitutionReconstitute with 100 µl sterile water. PBS containing at least 0.1% BSA should be used for further dilutions.
Delta transmembrane LIGHT
Herpes virus entry mediator ligand
Herpesvirus entry mediator A
Herpesvirus entry mediator ligand
herpesvirus entry mediator-ligand
Ligand for herpesvirus entry mediator
Tumor necrosis factor (ligand) superfamily, member 14
Tumor necrosis factor ligand superfamily member 14
Tumor necrosis factor ligand superfamily, member 14
Tumor necrosis factor receptor like 2
tumor necrosis factor receptor-like 2
Tumor necrosis factor superfamily member 14
Tumor necrosis factor superfamily member LIGHT
FunctionCytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Tissue specificityPredominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines.
Sequence similaritiesBelongs to the tumor necrosis factor family.
Post-translational modificationsN-glycosylated. The soluble form of isoform 1 derives from the membrane form by proteolytic processing.
Cellular localizationCytoplasm; Secreted and Cell membrane.