The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Leucine rich repeat and Ig domain containing 1
Leucine rich repeat neuronal 6A
Leucine rich repeat neuronal protein 1
Leucine rich repeat neuronal protein 6A
Leucine-rich repeat and immunoglobilin domain-containing protein 1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
Leucine-rich repeat neuronal protein 1
Leucine-rich repeat neuronal protein 6A
LRR and Ig domain containing Nogo Receptor interating protein
Nogo Receptor interacting protein
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.
Expressed exclusively in the central nervous system. Highest level in the in amygdala, hippocampus, thalamus and cerebral cortex. In the rest of the brain a basal expression seems to be always present. Up-regulated in substantia nigra neurons from Parkinson disease patients.