Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab93010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityBinds with high affinity to certain members of the low-density lipoprotein (LDL) receptor family such as LRP, gp330/megalin, and the very low-density lipoprotein (VLDL) receptor.
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 90 % SDS-PAGE.
    This endotoxin level in this preparation has been reduced to 22 EU/mg by chromatography.
  • FormLiquid
  • Additional notesSpectrophotometric Data: Epsilon0.1% = 0.926 Intact protein naturally cleaves into ~26 kDa C-terminal portion and ~13 kDa N-terminal fragment. Fragments can be removed by HPLC.Binds with high affinity to certain members of the low-density lipoprotein (LDL) receptor family such as LRP, gp330/megalin, and the very low-density lipoprotein (VLDL) receptor.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.15M Sodium chloride, 0.0067M PBS, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 39 kDa receptor-associated protein
    • A2MRAP
    • A2RAP
    • Alpha 2 macroglobulin receptor associated protein
    • Alpha 2 MRAP
    • Alpha-2-macroglobulin receptor-associated protein
    • Alpha-2-MRAP
    • AMRP_HUMAN
    • HBP44
    • Lipoprotein receptor associated protein
    • Low density lipoprotein receptor related protein associated protein 1
    • Low density lipoprotein receptor-related protein-associated protein 1
    • Low density lipoprotein related protein associated protein 1
    • Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein
    • low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1)
    • Lrpap1
    • MGC138272
    • MRAP
    • MYP23
    • RAP
    see all
  • FunctionInteracts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
  • Involvement in diseaseNote=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.
  • Sequence similaritiesBelongs to the alpha-2-MRAP family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationEndoplasmic reticulum. Cytoplasm. Cell surface. Intracellular and associated with cell surface receptors. Found in the endoplasmic reticulum.
  • Information by UniProt

References for Recombinant human LRPAP1 protein (ab93010)

ab93010 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"