Recombinant Mouse TIMP2 protein (Tagged-His Tag) (ab192281)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Tags: His tag C-Terminus
Description
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Product name
Recombinant Mouse TIMP2 protein (Tagged-His Tag)
See all TIMP2 proteins and peptides -
Purity
> 95 % SDS-PAGE.
Affinity chromatography is used to purify -
Endotoxin level
< 1.000 Eu/µg -
Expression system
HEK 293 cells -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
SCS PVHPQQAFCN ADVVIRAKAVSEKEVDSGND IYGNPIKRIQ YEIKQIKMFK GPDKDIEFIYTAPSSAVCGV SLDVGGKKEY LIAGKAEGDG KMHITLCDFI VPWDTLSITQ KKSLNHRYQM GCECKITRCP MIPCYISSPD ECLWMDWVTE KSINGHQAKF FACIKRSDGSCAWYRGAAPP KQEFLDIEDP -
Predicted molecular weight
19 kDa including tags -
Amino acids
27 to 220 -
Tags
His tag C-Terminus
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Specifications
Our Abpromise guarantee covers the use of ab192281 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% Phosphate Buffer
0.2 µM filtered solution -
ReconstitutionDissolve protein in 1 x PBS to a concentration no less than 100ug/ml
General Info
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Alternative names
- CSC 21K
- CSC-21K
- CSC21K
see all -
Function
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. -
Sequence similarities
Belongs to the protease inhibitor I35 (TIMP) family.
Contains 1 NTR domain. -
Post-translational
modificationsThe activity of TIMP2 is dependent on the presence of disulfide bonds. -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab192281 has not yet been referenced specifically in any publications.