Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMEIPPTNYPA SRAALVAQNY INYQQGTPHR VFEVQKVKQA SMEDIPGRGH KYRLKFAVEE IIQKQVKVNC TAEVLYPSTG QETAPEVNFT FEGETGKNPD EEDNTFYQRL KSMKEPLEAQ NIPDNFGNVS PEMTLVLHLA WVACGYIIWQ NSTEDTWYKM VKIQTVKQVQ RNDDFIELDY TILLHNIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEVQ LE

Associated products

Specifications

Our Abpromise guarantee covers the use of ab87145 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab87145 was purified using conventional chromatography. Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method )
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, pH 7.5

General Info

  • Alternative names
    • ECI
    • Endogenous carboxypeptidase inhibitor
    • Latexin
    • Latexin protein
    • LXN
    • LXN_HUMAN
    • MUM
    • Protein MUM
    • TCI
    • Tissue carboxypeptidase inhibitor
    see all
  • FunctionHardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4.
  • Tissue specificityHighly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.
  • Sequence similaritiesBelongs to the protease inhibitor I47 (latexin) family.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant Human LXN protein images

  • 15% SDS-PAGE showing ab87145 (3ug)

References for Recombinant Human LXN protein (ab87145)

This product has been referenced in:
  • Xue ZX  et al. Latexin inhibits the proliferation of CD133+ miapaca-2 pancreatic cancer stem-like cells. World J Surg Oncol 12:404 (2014). Functional Studies . Read more (PubMed: 25551472) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"