Recombinant Human LXR beta protein (ab81919)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab81919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    1 unit equals 1 nanogram of purified protein.
  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes
    1 unit equals 1 nanogram of purified protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • Liver X nuclear receptor beta
    • Liver X receptor beta
    • LX receptor beta
    • LXR b
    • LXR beta
    • LXRB
    • NER
    • NER I
    • NER1
    • NR1H 2
    • NR1H2
    • NR1H2_HUMAN
    • Nuclear orphan receptor LXR beta
    • Nuclear receptor NER
    • Nuclear receptor subfamily 1 group H member 2
    • OR-1
    • Oxysterols receptor LXR-beta
    • RIP15
    • Steroid hormone nuclear receptor NER
    • Ubiquitously-expressed nuclear receptor
    • UNR
    see all
  • Function
    Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab81919 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Both proteins have the same sequence of full length LXR-beta.

However, please note that ab81924 has a 6 x Histag on its N-terminus and ab81919 is a GST-fusion to LXR-beta.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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