Recombinant Human LXR beta protein (ab81924)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab81924 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    1 unit equals 1 nanogram of purified protein.
  • Applications

    SDS-PAGE

    EMSA

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Liquid
  • Additional notes
    1 unit equals 1 nanogram of purified protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

General Info

  • Alternative names
    • Liver X nuclear receptor beta
    • Liver X receptor beta
    • LX receptor beta
    • LXR b
    • LXR beta
    • LXRB
    • NER
    • NER I
    • NER1
    • NR1H 2
    • NR1H2
    • NR1H2_HUMAN
    • Nuclear orphan receptor LXR beta
    • Nuclear receptor NER
    • Nuclear receptor subfamily 1 group H member 2
    • OR-1
    • Oxysterols receptor LXR-beta
    • RIP15
    • Steroid hormone nuclear receptor NER
    • Ubiquitously-expressed nuclear receptor
    • UNR
    see all
  • Function
    Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References for Recombinant Human LXR beta protein (ab81924)

ab81924 has not yet been referenced specifically in any publications.

Product Wall

Both proteins have the same sequence of full length LXR-beta.

However, please note that ab81924 has a 6 x Histag on its N-terminus and ab81919 is a GST-fusion to LXR-beta.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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