Overview

  • Product nameRecombinant human MAGE 1 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Molecular weight60 kDa including tags

Specifications

Our Abpromise guarantee covers the use of ab75539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityMAGE 1 antibody reactive.
  • Applications

    Western blot

    ELISA

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Antigen MZ2 E
    • Antigen MZ2-E
    • Cancer/testis antigen 1.1
    • cancer/testis antigen family 1, member 1
    • CT1.1
    • MAGA1_HUMAN
    • MAGE 1 antigen
    • MAGE-1 antigen
    • MAGE1
    • MAGE1A
    • MAGEA1
    • Melanoma antigen 1
    • Melanoma antigen family A 1
    • Melanoma antigen family A 1 (directs expression of antigen MZ2 E)
    • Melanoma antigen MAGE 1
    • Melanoma associated antigen 1
    • Melanoma associated antigen MZ2 E
    • Melanoma-associated antigen 1
    • MGC9326
    see all
  • FunctionMay be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
  • Tissue specificityExpressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.
  • Sequence similaritiesContains 1 MAGE domain.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt

References for Recombinant human MAGE 1 protein (ab75539)

ab75539 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"