Recombinant human MAP3K6 protein (ab125621)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      67 kDa including tags
    • Amino acids
      620 to 950

Associated products

Specifications

Our Abpromise guarantee covers the use of ab125621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The specific activity of ab125621 was determined to be 10 nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • Form
    Liquid
  • Additional notes

    ab64311 (Myelin Basic Protein protein) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Apoptosis signal regulating kinase 2
    • Apoptosis signal-regulating kinase 2
    • ASK2
    • EC 2.7.11.25
    • M3K6_HUMAN
    • MAP3K6
    • MAPKKK6
    • MEKK6
    • MGC125653
    • MGC20114
    • Mitogen-activated protein kinase kinase kinase 6
    see all
  • Function
    Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

Images

  • The specific activity of ab125621 was determined to be 10 nmol/min/mg by Kinase Assay.
  • SDS-PAGE analysis of ab125621.

References

ab125621 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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