Recombinant Human MAP3K9 protein (ab116944)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      EFPRLPDPNVVFPPTPRRWNTQQDSTLERPKTLEFLPRPRPSANRQRLDP WWFVSPSHARSTSPANSSSTETPSNLDSCFASSSSTVEERPGLPALLPFQ AGPLPPTERT
    • Molecular weight
      38 kDa including tags
    • Amino acids
      971 to 1080

Specifications

Our Abpromise guarantee covers the use of ab116944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • M3K9_HUMAN
    • Map3k9
    • MEKK9
    • Mitogen activated protein kinase kinase kinase 9
    • Mitogen-activated protein kinase kinase kinase 9
    • Mixed lineage kinase 1
    • Mixed lineage kinase 1 (tyr and ser/thr specificity)
    • MLK1
    • PRKE1
    see all
  • Function
    Activates the JUN N-terminal pathway.
  • Tissue specificity
    Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE showing ab116944 at approximately 37.73kDa stained with Coomassie Blue.

References

ab116944 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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