This product is an active protein and may elicit a biological response in vivo, handle with caution.
Kinase homologous to SPS1/STE20
MAPK/ERK kinase kinase kinase 5
MEK kinase kinase 5
RelevanceMAP4K5, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress. It appears to act upstream of the JUN N-terminal pathway. MAP4K5 interacts with both SH3 domains of the adapter proteins CRK and CRKL. This cytoplasmic protein is ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
Recombinant human MAP4K5 protein images
SDS-PAGE - MAP4K5 protein (Active) (ab56636)
SDS Page analysis of ab56636
Functional Studies - MAP4K5 protein (Tagged) (ab56636)
Kinase Assay using Myelin Base protein as the substrate. Specific Activity: 86 nmol/min/mg.
References for Recombinant human MAP4K5 protein (ab56636)
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