Overview

  • Product nameRecombinant human MAP4K6 protein
  • Protein lengthProtein fragment

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids1 to 320

Associated products

Specifications

Our Abpromise guarantee covers the use of ab55712 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific Activity: 19 nmol/min/mg
  • Applications

    Functional Studies

    SDS-PAGE

  • FormLiquid
  • Additional notes

    ab43614 (Human Myelin Basic Protein full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • B55
    • GCK family kinase MiNK
    • hMINK
    • Map4k6
    • MAPK/ERK kinase kinase kinase 6
    • MEK (MAP/ERK) kinase kinase 6
    • MEK kinase kinase 6
    • MEKKK6
    • MGC21111
    • MINK
    • MINK 1
    • MINK1
    • Misshapen like kinase 1
    • Misshapen NIKs Related kinase
    • Misshapen/NIK related kinase
    • Mitogen activated protein kinase kinase kinase kinase 6
    • RP23-122P1.6
    • Ysk2
    • ZC3
    see all
  • RelevanceMAP4K6 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. These kinases regulate a wide variety of cellular processes by coupling cell surface receptors to MAPK pathways. This kinase appears to act upstream of the JUN N-terminal pathway and may be involved in brain development. It may also play a role in the response to environmental stress, in cytoskeleton reorganization, cell adhesion, and cell motility. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
  • Cellular localizationCytoplasm. Cell junction; synapse; postsynaptic cell membrane; postsynaptic density. Cell projection; axon. Cell projection; dendrite. Isoform 4: Golgi apparatus

Recombinant human MAP4K6 protein images

  • SDS-PAGE analysis of ab55712 with molecular weight markers. Approximate molecular weight 61kDa.
  • Kinase assay using ab55712. Specific activity: 19 nmol/min/mg.

References for Recombinant human MAP4K6 protein (ab55712)

ab55712 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"