Recombinant Human MASPIN protein (ab125796)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP36952
    • SpeciesHuman
    • SequenceMDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCS
    • Molecular weight42 kDa
    • Amino acids1 to 375

Specifications

Our Abpromise guarantee covers the use of ab125796 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Purity> 97 % SDS-PAGE.
    ab125796 is purified by proprietary chromatographic techniques. Purity is greater than 97.0% as determined by RP-HPLC and SDS-PAGE.
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    pH: 7.00
    Constituent: 99% PBS

  • ReconstitutionIt is recommended to reconstitute ab125796 in sterile ultra pure water not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Upon reconstitution ab125796 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

General Info

  • Alternative names
    • Maspin
    • Ovalbumin
    • Peptidase inhibitor 5
    • PI-5
    • PI5
    • Protease inhibitor 5
    • protease inhibitor 5 (maspin)
    • Serine (or cysteine) peptidase inhibitor, clade B, member 5
    • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5
    • Serpin B5
    • serpin family B member 5
    • Serpin peptidase inhibitor
    • Serpin peptidase inhibitor, clade B (ovalbumin), member 5
    • Serpinb5
    • SPB5_HUMAN
    • Spi5
    • Spi7
    see all
  • FunctionTumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
  • Tissue specificityNormal mammary epithelial cells.
  • Sequence similaritiesBelongs to the serpin family. Ov-serpin subfamily.
  • Cellular localizationSecreted > extracellular space.
  • Information by UniProt

References for Recombinant Human MASPIN protein (ab125796)

ab125796 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"