Recombinant Human MAST205 protein (ab161545)

Overview

  • Product name
    Recombinant Human MAST205 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKAHERSESSEVAFVMQL VKKLMIIIARPARLLECLEFDPEEFYHLLEAAEGHAKEGQGIKCDIPRYI VSQLGLTRDPLEEMAQLSSCDSPDTPETDDSIEGHGASLPSKKTPSEEDF ETIKLISNGAYGAVFLVRHKSTRQRFAMKKINKQNLILRNQIQQAFVERD ILTFAENPFVVSMFCSFDTKRHLCMVMEYVEGGDCATLLKNIGALPVDMV RLYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLM SLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMG IILYEFLVGCVPFFGDTPEELFGQVISDEIVWPEGDEALPPDAQDLTSKL LHQNPLERLGTGSAYEVKQHPFFTGLDWTGLLRQKAEFIPQLESEDDTSY FDTRSERYHHMDSEDEEEVSEDGCLEIRQFSSCSPRFNKVYSSMERLSLL EERRTPPPTKRSLSEEKEDHSDGLAGLKGRDRSWVIGSPEILRKRLSVSE SSHTESDSSPPMTVRRRCSGLLDAPRFPEGPEEASSTLRRQPQEGIWVLT PPSGEGVSGPVTEHSGEQRPKLDEEAVGRSSGSSPAMETRGRGTSQLAEG ATAKAISDLAVRRARHRLLSGDSTEKRTARPVNKVIKSASATALSLLIPS EHHTCSPLASPMSPHSQSSNPSSRDSSPRSMASPCGPFASTWVTPMSTPC TIWCGTWRMEVRPVRQGFVKVTSSPMSMGNLCMAWCTRRWWS
    • Amino acids
      1 to 792
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161545 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • EC 2.7.11.1 3
    • FLJ39200
    • KIAA0807
    • MAST 2
    • MAST 205
    • Mast2
    • MAST2_HUMAN
    • Microtubule associated serine/threonine kinase 2
    • Microtubule associated testis specific serine/threonine protein kinase
    • Microtubule-associated serine/threonine-protein kinase 2
    • MTSSK
    • OTTHUMP00000009697 2
    • OTTHUMP00000046616
    • RP4 533D7.1
    • RP4-533D7.1 2
    see all
  • Function
    Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.
  • Tissue specificity
    Abundant in the testis.
  • Sequence similarities
    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 PDZ (DHR) domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination.
  • Cellular localization
    Cytoplasm > cytoskeleton. Cell membrane. Recruited to the sub-membranous area on interaction with CDHR2.
  • Information by UniProt

Images

  • ab161545 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab161545 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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