The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Csk homologous kinase
Csk type protein tyrosine kinase
Hematopoietic consensus tyrosine lacking kinase
Hematopoietic consensus tyrosine-lacking kinase
Hydroxyaryl protein kinase
HYL tyrosine kinase
Leukocyte carboxyl terminal src kinase related
Megakaryocyte associated tyrosine kinase
Megakaryocyte associated tyrosine protein kinase
Megakaryocyte-associated tyrosine-protein kinase
Protein kinase HYL
Tyrosine kinase MATK
Tyrosine protein kinase CTK
Tyrosine-protein kinase CTK
Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
Expressed in various myeloid cell lines, detected in brain and lung.
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily. Contains 1 protein kinase domain. Contains 1 SH2 domain. Contains 1 SH3 domain.
Phosphorylated upon DNA damage, probably by ATM or ATR.