Recombinant Human MBD4 protein (ab126003)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionO95243
    • SpeciesHuman
    • Molecular weight26 kDa
    • Amino acids68 to 300

Specifications

Our Abpromise guarantee covers the use of ab126003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

    Constituents: 0.32% Tris HCl, 0.58% Sodium chloride

  • ReconstitutionReconstitute with water to desired concentration.

General Info

  • Alternative names
    • 3 N(4) ethenocytosine glycosylase
    • G/5 fluorouracil mismatch glycosylase with biphasic kinetics
    • G/T mismatch glycosylase
    • G/U mismatch glycosylase
    • MBD 4
    • MBD4
    • MBD4_HUMAN
    • MED 1
    • MED1
    • Methyl CpG binding domain protein 4
    • Methyl CpG binding endonuclease 1
    • Methyl CpG binding protein MBD4
    • Methyl-CpG-binding domain protein 4
    • Methyl-CpG-binding endonuclease 1
    • Methyl-CpG-binding protein MBD4
    • Mismatch specific DNA N glycosylase
    • Mismatch-specific DNA N-glycosylase
    • Putative methyl CpG binding protein
    see all
  • FunctionMismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
  • Sequence similaritiesContains 1 MBD (methyl-CpG-binding) domain.
  • Cellular localizationNucleus.
  • Information by UniProt

References for Recombinant Human MBD4 protein (ab126003)

ab126003 has not yet been referenced specifically in any publications.

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