Membrane bound O acyltransferase domain containing 2
Membrane-bound O-acyltransferase domain-containing protein 2
O acyltransferase (membrane bound) domain containing 2
O-acyltransferase domain-containing protein 2
Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
Expressed in neutrophils.
Lipid metabolism; phospholipid metabolism.
Belongs to the membrane-bound acyltransferase family.