Recombinant Human MC4 Receptor protein (ab112318)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP32245
    • SpeciesHuman
    • SequenceMVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQ
    • Molecular weight30 kDa including tags
    • Amino acids1 to 43
    • TagsGST tag N-Terminus

Associated products

Specifications

Our Abpromise guarantee covers the use of ab112318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • FormLiquid
  • Additional notesBest use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • MC4-R
    • MC4R
    • MC4R_HUMAN
    • Melanocortin 4 receptor
    • Melanocortin receptor 4
    • MGC126851
    • MGC138197
    see all
  • FunctionReceptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase.
  • Tissue specificityBrain, placental, and gut tissues.
  • Involvement in diseaseDefects in MC4R are a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt

Recombinant Human MC4 Receptor protein images

  • ab112318 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References for Recombinant Human MC4 Receptor protein (ab112318)

ab112318 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"