Recombinant Human MCK10 protein (ab80373)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids444 to 913

Associated products

Specifications

Our Abpromise guarantee covers the use of ab80373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 50mM Tris HCl, 3mM DTT, 150mM Sodium chloride, 0.1mM EDTA, 0.1mM PMSF, 0.1mM EGTA, pH 7.5

General Info

  • Alternative names
    • CAK
    • CD 167
    • CD167
    • CD167 antigen-like family member A
    • CD167a
    • Cell adhesion kinase
    • DDR
    • DDR 1
    • DDR1
    • DDR1_HUMAN
    • Discoidin domain receptor
    • Discoidin domain receptor tyrosine kinase 1
    • Discoidin receptor tyrosine kinase
    • Discoidin receptor tyrosine kinase isoform a
    • EDDR 1
    • EDDR1
    • Epithelial discoidin domain receptor 1
    • Epithelial discoidin domain-containing receptor 1
    • Epithelial specific receptor kinase
    • HGK2
    • Mammarian carcinoma kinase 10
    • Mammary carcinoma kinase 10
    • MCK-10
    • MCK10
    • NEP
    • Neuroepithelial tyrosine kinase
    • Neurotrophic tyrosine kinase receptor type 4
    • NTRK 4
    • NTRK4
    • OTTHUMP00000029343
    • OTTHUMP00000029344
    • OTTHUMP00000029345
    • OTTHUMP00000029346
    • OTTHUMP00000029347
    • OTTHUMP00000164863
    • OTTHUMP00000164867
    • OTTHUMP00000222080
    • Protein-tyrosine kinase 3A
    • Protein-tyrosine kinase RTK-6
    • PTK 3
    • PTK 3A protein tyrosine kinase 3A
    • PTK3
    • PTK3A
    • Receptor tyrosine kinase NEP
    • RTK 6
    • RTK6
    • TRK E
    • TRKE
    • Tyrosine kinase DDR
    • Tyrosine kinase receptor E
    • Tyrosine-protein kinase CAK
    see all
  • FunctionMay be involved in cell-cell interactions and recognition.
  • Tissue specificityDetected in T-47D, MDA-MB-175 and HBL-100 breast carcinoma cells, A431 epidermoid carcinoma cells, SW48 and SNU-C2B colon carcinoma cells and Hs 294T melanoma cells (at protein level). Expressed at low levels in most adult tissues and is highest in the brain, lung, placenta and kidney. Lower levels of expression are detected in melanocytes, heart, liver, skeletal muscle and pancreas. Abundant in breast carcinoma cell lines. In the colonic mucosa, expressed in epithelia but not in the connective tissue of the lamina propria. In the thyroid gland, expressed in the epithelium of the thyroid follicles. In pancreas, expressed in the islets of Langerhans cells, but not in the surrounding epithelial cells of the exocrine pancreas. In kidney, expressed in the epithelia of the distal tubules. Not expressed in connective tissue, endothelial cells, adipose tissue, muscle cells or cells of hematopoietic origin.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 1 F5/8 type C domain.
    Contains 1 protein kinase domain.
  • DomainThe Gly/Pro-rich domains may be required for an unusual geometry of interaction with ligand or substrates.
  • Cellular localizationSecreted and Membrane.
  • Information by UniProt

Recombinant Human MCK10 protein images

  • 10% SDS-PAGE showing ab80373 at approximately 76kDa (6µg).

References for Recombinant Human MCK10 protein (ab80373)

ab80373 has not yet been referenced specifically in any publications.

Product Wall

Please find attached the sequence for this protein and the tag.

For an arbitrary protein that contains the tag, if I understand you correctly, there are a number of choices, but ab54334 will serve:

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"