The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
This protein can be used for neutralization assays.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.1% SDS, PBS
Lymphocyte antigen 96
MD 2 protein
Myeloid differentiation protein 2
Protein MD 2
FunctionCooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.